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Case Report

A fatal Acremonium falciforme peritonitis

Yasemin Ay Altintop1, Ayse Nedret Koc

   

Abstract
A case of Acremonium falciforme peritonitis in a 50-year-old man with a 10-year history of end stage renal disease that was on Continuous Ambulatory Peritoneal Dialysis for 8 years is reported. The aim of this report is to remind the clinician that in resistant and life-threatening peritonitis, A. falciforme may be the cause. This fungus was identified as A. falciforme in culture by its characteristic colonies and microscopic morphological findings. In vitro fluconazole and amphotericin B minimum inhibitory concentrations (MICs) were found as 6 and 0.125 μg/mL respectively. First fluconazole and then amphotericin B was administered, but patient was deceased on day 10 of amphotericin B therapy. This indicates that more antifungal susceptibility studies should be done before making a comment about in vivo and in vitro concordance of susceptibility of filamentous fungi.

Key words: Acremonium falciforme, peritonitis, amphotericin B, fluconazole, itraconazole, voriconazole, ketoconazole

Med-Science. 2018; 7(1): 222-224

 
Medicine Science Vol:7 Issue:1 Year:2018 PP:1–246
Posted in Vol: 7 Issue: 1 Year: 2018 March pp: 1–246

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