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Original Article

Is there really association between lichen planus and hepatitis C?

Fatma Tuncez Akyurek, Gulcan Saylam Kurtipek

   

Abstract
Lichen planus (LP) is a T-cell mediated dermatosis with unknown etiology that is affecting the skin, oral mucosa, nail and hair follicle. Although the cause is not known, there are many articles in the literature that show the association between LP and hepatitis-C, especially oral LP. However, this association may vary according to geographical regions. We aimed to determine whether such an epidemiological relationship exists in a group of patients with lichen planus who applied to our clinic. The records of 145 patients who were admitted to our clinic between March 2014 and 2018 and diagnosed clinically and histopathologically as LP were retrospectively reviewed and none of them had anti-HCV positivity.
Discussion: The prevalence of chronic hepatitis C in oral LP patients has been reported to vary between geographical regions. Based on the literature and books, hepatitis-C screenings were performed in patients who were followed up with LP clinically and histopathologically in our clinic for a long time. We did not find any association between HCV and LP in our study. This could be attributed to a lower prevalence of HCV in our country or other triggering factors contributing in our cases.

Key words: Lichen planus, HCV, association

Med-Science. 2019; 8(4): 913-5

 
Medicine Science Vol:9 Issue:1 Year:2020 PP:1–288
Posted in Vol: 8 Issue: 4 Year: 2019 December pp: 774-1046

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