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Original Article

Association between some hematological parameters and in vitro fertilization outcomes

Ayse Nur Yildirim, Osman Nuri Keles


The aim of this study was to determine the effects of some hematological parameters on fertilization success, embryo quality and pregnancy rates in the in vitro fertilization (IVF) treatment. 50 infertile couples aged 22-46 years who were admitted to Ataturk University Research Hospital for IVF treatment were included in the study. The number of fertilized oocytes, embryo quality, clinic pregnancy rate were determineted and compared with hematological parameters. In the male petients, the platelet distribution width (PDW) value was negatively correlated with the fertilization rate (rp = -0.341*; p=0.015). An negative relationship between the transplantable embryo rate and the mean corpuscular volume (MCV) value was observed (rp = -0.320*; p = 0.024) in the male. While the hemoglobin (HGB) value was negatively correlated with the fertilization rate (rp=-0.332*; p=0.019), the red cell distribution width (RDW) value was positively correlated with the fertilization rate (rp = 0.359*; p=0.010) in female petients. In addition, significant correlations were found between PDW value both good quality embryo rate (regression coefficient : -19.808, p = 0.007) ( corrected as -19.808) and transplantable embryo rate (regression coefficient : -16.855, p = 0.033) (corrected as -16.855) in female petients. In conclusion, changes in PDW values of female patients significantly affect embryo quality, may result pregnancy failure and abnormal embryo and fetus development during pregnancy.

Key words: Fertilization in vitro, embryo, pregnancy, blood cell count

Med-Science. 2020; 9(3): 619-24

Medicine Science Vol:9 Issue:3 Year:2020 PP:526–801
Posted in Vol: 9 Issue: 3 Year: 2020 September pp: 526–801

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