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Investigation of antiphospholipid antibody syndrome markers in the etiology of recurrent miscarriage

Vildan Gorgulu, Orhan Cem Aktepe, Birol Safak.


This study aimed to determine the markers of antiphospholipid antibody syndrome (APS), which has an important place in the etiology of recurrent miscarriage, and to provide guidance for the treatment of the related disorders. This prospective observational study was performed on 120 female patients admitted to the Obstetrics and Gynecology outpatient clinics due to recurrent pregnancy loss. Blood samples were analyzed using the Enzyme-Linked Immunosorbent Assay (ELISA) technique to find out the levels of APS-associated anticardiolipin (ACA), anti-beta2-glycoprotein I (aβ2GPI), anti-annexin V (aANXV), anti-prothrombin (aPT), and antiphosphatidylserine (aPS) antibodies. A statistically significant difference was found between increased age groups and the number of miscarriages (p=0.03, p

Key words: Antiphospholipid, recurrent miscarriages, etiology, anticardiolipin antibody

Med-Science. 2021; 10(1): 184-90
Medicine Science Vol:10 Issue:1 Year:2021 PP:1–271
Posted in Vol: 10 Issue: 1 Year: 2021 March pp:1–271

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