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Original Article

Taste buds degeneration induced by lingual artery spasm in subarachnoid hemorrhage in rabbits

Cengiz Ozturk, Ismail Malkoc, Rabia Demirtas, Mehmet Dumlu Aydin

   

Abstract
The role of the vasospasm induced by subarachnoid hemorrhage (SAH) in tongue taste bud degeneration is well established; however, the role of lingual artery spasm induced by SAH in that has not been efficiently studied. It was aimed to investigate the relationship between the taste buds degeneration and lingual artery spasm after SAH. Seventeen rabbits were randomizied into three groups: untouched control group (n=5), physiologic serum saline injected group (SHAM; n=6), and subarachnoid hemorrhage group (study; n=6). Experimental SAH was performed by injection 0.75 ml auricular arterial homologous blood was injected into cisterna magna three times in two weeks. After three weeks, all the rabbits were sacrificed and their tongues were removed under general anesthesia following intracardiac formalin injections. Normal and degenerated taste buds numbers and lingual artery vasospasm indexes were examined stereologically. Results were analyzed statistically with the Kruskal Wallis and the Mann Whitney U tests. Significance was accepted as p

Key words: Subarachnoid hemorrhage, lingual artery spasm, taste buds degeneration, experimental

Med-Science. 2021; 10(2): 560-3

Medicine Science Vol:10 Issue:2 Year:2021 PP:272–669
Posted in Vol: 10 Issue: 2 Year: 2021 June pp: 272–669

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