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Stevens-Johnson Syndrome: Case Presentation Related to the Use of Antiepileptic Medications..

Case Report

Stevens-Johnson Syndrome: Case Presentation Related to the Use of Antiepileptic Medications..

Nur Efe Iris, Funda Simsek, Taner Yildirmak, Arzu Kanturk, Muret Ersoz Arat

   

Abstract
Stevens-Johnson Syndrome is an acute shit allergic reaction that can be life-threatening. Here we present a case of Stevens-Johnson Syndrome that has developed due to the use of combined medications. The 18-year-old female patient was hospitalized with the complaints of fever, chills and widespread eruptions all over her body. In her history she had generalized epileptic seizures that have been treated with valproate for the last five years; however, as the seizures could not be controlled , Lamotrigine was added to her treatment about a month ago. She was also on Paroxetine for her hallucinations. She had generalized desquamation on the face, exfoliating brown squames and plaques on the forehead and the cheeks, erythema and blurring around both eyes, redness, xerosis and desqua and white-coloured membranes of the lips, brown-pigmented and itchy papules and plaques and some vesicles on her back and hips that were also seen all around her body.. With these findings, the patient was evaluated as having drug eruptions (SJS) and transferred to the intensive care unit. With steroid treatment , the lesions regressed quickly. When Lamotrigine was added to her treatment regimen, she had been using valproate for 5 years; she had not developed skin lesions, that is why valproate was not considered as an ethiological factor. Valproate is known to increase the viability of Lamotrigine by decreasing its glucuronidation.Use of Paroxetine is regarded as a risk factor for SJS also.. When combining medications, an attempt should be made not to combine such medications if possible.

Key words: Lamotrigine, paroxetine, Stevens-Johnson Syndrome, valproate

Med-Science. 2016; 5(Supplement 1): 1-7

 
Medicine Science Vol:5 Supp. Year:2016 PP:1-223

Unilateral Atypic Foramen Ovale in Dried Human Skull: Surgical Importance of a Rare Bone Variation

Case Report

Unilateral Atypic Foramen Ovale in Dried Human Skull: Surgical Importance of a Rare Bone Variation

Deniz Senol, Mahmut Cay, Nesibe Yilmaz, Mustafa Canbolat, Evren Kose, Davut Ozbag

   

Abstract
Foramen ovale (FO) serves as an important landmark for neurosurgeons in the surgical procedures of the trigeminal nerve. FO is the transition point between intracranial and extracranial structures. The information about anatomical variations of foramen ovale have surgical importance in different methods such as percutaneous trigeminal rhizotomy, biopsy of cavernous sinus tumour and anaesthesia of the mandibular nerve. FO variation is quite rare. It is unknown by many researchers and clinicians. It is thought that divided FO variations emerge as a result of the ossification of pterygospinous ligament. Clinicians must know that such variation may occur in surgical operations on skull base.

Key words: Foraman ovale, variation, sphenoid bone, base of skull, ossification

Med-Science. 2016; 5(Supplement 1): 8-13

 

Kimmerle’s Anomaly: Posterior Osseous Bridging of Atlas

Case Report

Kimmerle’s Anomaly: Posterior Osseous Bridging of Atlas

Deniz Senol, Mustafa Canbolat, Sumeyye Ulutas, Mahmut Cay, Songul Cuglan, Evren Kose, Davut Ozbag

   

Abstract
Kimmerle’s anomaly is a rare and serious pathology of the 1st cervical vertebra, which may sometimes lead to hardly explicable changes in vertebrobasilar circulation. Also known as ponticulus posticus (PP), this phenomenon encircles the vertebral artery and suboccipital nerve and is associated with vertigo, vertebro-basilar insufficiency, neck pain, shoulder pain and cervicogenic headache symptoms. It can also lead to migraine as a result of its interaction with dura. As the knowledge of this variant by clinicians is important for obtaining a fast result in the treatment, it should also be taken into account in surgical approaches so as not to harm the vessels and nerves in this area.

Key words: Anomaly, ponticulus posticus, Kimmerle, atlas

Med-Science. 2016; 5(Supplement 1): 14-20

 

Plasma 25-hydroxyvitamin D Status and Tooth Loss: A Case Report with Review of Literature

Case Report

Plasma 25-hydroxyvitamin D Status and Tooth Loss: A Case Report with Review of Literature

Ferit Celik, Fulden Sarac, Sumru Savas, Fehmi Akcicek

   

Abstract
Vitamin D is needed for uptake of calcium from the gut and reabsorption of calcium from the kidneys and bone to maintain adequate plasma calcium concentrations for bone mineralization. Many studies have investigated the association between vitamin D status and periodontal diseases. Recently, Third National Health and Nutrition Examination Survey (NHANES III, 1988–1994) reported that there was an inverse association between serum 25-hydroxyvitamin D concentrations and gingival inflammation and periodontal clinical attachment level. Maintenance of vitamin D intake near or above the recommendations, whether through diet or supplementation, could be a safe and effective way of reducing periodontal disease prevalence. People taking combined dietary supplements of vitamin D and calcium tended to have better periodontal health, with shallower probing depth, less attachment loss, and less alveolar bone loss. In tis case, a 44 year old female was referred for an opinion regarding a six-months history of progressive tooth loss. This case report shows that tooth loss might be seen in patients with D vitamin deficiency.

Key words: 25-hydroxyvitamin D, calcium, tooth loss

Med-Science. 2016; 5(Supplement 1): 21-8

 

Malposition of Subclavian Vein Catheter: A case report and review of literature

Case Report

Malposition of Subclavian Vein Catheter: A case report and review of literature

Omer Karaca, Ali Ahiskalioglu, Elif Oral Ahiskalioglu, Ilker Ince, Mehmet Aksoy

   

Abstract
The insertion of central venous catheter (CVC) is used for different purposes among the patients. Seldinger method is the most common percutaneous access method for CVC insertion. During this procedure, direction of the catheter to an unwanted vein is a rare, but a serious complication. In order to reduce complications, it is essential that the staff applying the central venous catheterization should be experienced; use the accurate technique and the location of the catheter be displayed by using radiological method after the procedure. We aimed to discuss the malposition of the CVC in two cases in the light of the information in the literature.

Key words: Complication, central venous cannulation, malposition

Med-Science. 2016; 5(Supplement 1): 29-34

 

From Respiratory Distress to Diagnosis of Amyotrophic Lateral Sclerosis

Case Report

From Respiratory Distress to Diagnosis of Amyotrophic Lateral Sclerosis

Muhammet Emin Naldan, Pelin Aydin, Elif Oral Ahiskalioglu, Fatma Karakoc, Duygu Kara

   

Abstract
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease of motor neurons, which results in weakness and atrophy of voluntary skeletal muscles. ALS is the most common form of motor neuron disease (MND). It is currently incurable and treatment is largely limited to supportive care. Family history is associated with an increased risk of ALS. The disease usually does not affect cognitive abilities, but causes muscle weakness. Respiratory function in the early stages of the disease is generally normal, shortness of breath occurs as the disease progresses. This paper has been submitted about ALS patient who was diagnosed and treated in intensive care unit followed by severe respiratory failure.

Key words: Amyotrophic lateral sclerosis, respiratory failure

Med-Science. 2016; 5(Supplement 1): 35-40

 

Bilateral Lumbosacral Plexopathy Following Prostate Surgery: A Case Report [Prostat Cerrahisi Sonrasında Görülen Bilateral Lumbosakral Pleksopati: Bir Olgu Sunumu]

Case Report

Bilateral Lumbosacral Plexopathy Following Prostate Surgery: A Case Report [Prostat Cerrahisi Sonrasında Görülen Bilateral Lumbosakral Pleksopati: Bir Olgu Sunumu]

Ilker Ince, Mehmet Aksoy, Ali Ahiskalioglu, Muhammet Ahmet Karakaya, Haci Ahmet Alici

   

Abstract
Postoperative neurologic complications of anesthesia is often thought to develop as secondary. The first reason of bilateral lower limb paralysis after regional block is anesthesia. However, rare complications such as bilateral lumbosacral plexus injury may lead to the clinical presentation. In this current case, we aimed to discuss the propable causes of plexopathy and to present the patient who had urgent surgery again after open prostate surgery and who is with bilateral lumbosacral plexopathy.

Key words: Combined spinal-epidural anesthesia, bilateral lumbosacral plexopathy, complication

Med-Science. 2016; 5(Supplement 1): 41-7

 

Pneumocephalus Following Combined Spinoepidural Anesthesia: A Case Report

Case Report

Pneumocephalus Following Combined Spinoepidural Anesthesia: A Case Report

Emine Karaman, Duygu Kara, Ozgur Ozmen, Zakir Arslan

   

Abstract
Various complications may develop as a result of epidural anaesthesia. Pneumocephalus is a rare complication during epidural catheter insertion. In this case report, 61 years old patient was admitted for hip fracture and planned to have hip replacement surgery. Combined spinoepidural anesthesia was planned during surgery as anesthetic tehchnique. Epidural catheter was inserted for postoperative pain control. Forty-five minutes after the operation, he had a sudden blunt headache, and generalized tonic, clonic status for two minutes. We aimed to present a case of pneumocephalus after combined spinoepidural anesthesia.

Key words: Combined spinoepidural anethesia, epidural catheter insertion, pneumocephalus

Med-Science. 2016; 5(Supplement 1): 48-54

 

Herpes Gladiatorum: A Case Report

Case Report

Herpes Gladiatorum: A Case Report

Ragip Ismail Engin

   

Abstract
Herpes gladiatorum, is a skin infection caused by the Herpes simplex virus (HSV). It is generally seen in contact athletes such as wrestlers. Direct contact with the lesion may cause widespread herpetic lesions. These are mostly observed in the head-neck and upper extremities. The skin lesions may be accompanied by fever, fatigue, headaches, throat aches and lymphadenopathies. The diagnosis is generally based on presentation and the clinical basis. This article presents herpes gladiatorum, which is a form of herpes infection that occurs on close contact, which is identified in a patient who is a wrestler, along with the relevant literature.

Key words: Wrestlers, herpes gladiatorum, dermatology

Med-Science. 2016; 5(Supplement 1): 55-8

 

Erythema Dyschromicum Perstans: A Case Report

Case Report

Erythema Dyschromicum Perstans: A Case Report

Ragip Ismail Engin, Erdal Pala, Oya Nermin Sivrikoz

   

Abstract
Erythema dyschromicum perstans (EDP) is an acquired dermatosis characterized by ash gray (ashy dermatosis) or blue macules. It can appear at any ageö but is more common in young adults. Lesions may occur on the neck, chest arms and face, but most frequently on the back. It does not generally lead to subjective complaints, but may rarely cause itching. Diagnosis is made with clinical findings and can be corroborated by histopathological examination. This report describes the case of a 15-year-old female patient diagnosed with EDP and is intended to emphasize the need to include the condition at differential diagnosis.

Key words: Ashy dermatosis, erythema dyschromicum perstans, hyperpigmentation

Med-Science. 2016; 5(Supplement 1): 59-63