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The renal neoplastic lesions in non-functioning kidney patients who underwent simple nephrectomy

Original Article

The renal neoplastic lesions in non-functioning kidney patients who underwent simple nephrectomy

Selahattin Caliskan, Mustafa Sungur, Emrah Ozsoy, Orhan Koca

   

Abstract
The simple nephrectomy is usually performed in daily urology practice for the non-functioning kidney. The aim of this study is to determine the incidental malignancy rate of the patients who underwent nephrectomy procedure. In total, 258 patients were included in the study. The patients who underwent simple nephrectomy and diagnosed as renal tumor between January 2003 and March 2016 for the non-functioning kidney at our department were recorded. There were 258 patients in this study. Of these patients;123 were male and 134 were female patients. The mean age of the patients’ was 52.33+17.63 years. The presence of stone formation was detected in 92 patients (35.65%). The renal malignancy was reported in 9 patients.Among the patients with malignancy; 2 patients were female and 7 patients were male. The mean age of the patients was 54.77+8.81 years. The pathological examination revealed that 6 patients were transitional cell carcinoma (TCC) of the renal pelvis, 2 patients were renal cell carcinoma, one patient was cystic nephroma. Interestingly, nephrolithiasis was detected only in one patient. The prevalence of all malignancy and the malignant tumor was 3.48% and 3.10% in this study. The final pathology showed that there is a risk of malignancy fort he patients with the non-functioning kidney. The clinicians should be aware that the patient may be diagnosed as renal tumor after pathological examination.

Key words: Nephrectomy, neoplasia, prevelance

Med-Science. 2018; 7(2): 247-8

Medicine Science Vol:7 Issue:2 Year:2018 PP:247-468

Abnormal eating attitudes and the level of impulsiveness in morbid obese patients who are candidates for bariatric surgery

Original Article

Abnormal eating attitudes and the level of impulsiveness in morbid obese patients who are candidates for bariatric surgery

Lale Gonenir Erbay, Pelin Bozkurt

   

Abstract
Obesity is a chronic disease needs to be investigated not from the biological point of view alone, as it also has medical and psychological outcomes. While evaluating obese patients, we come across many psychopathological conditions. The present study aimed to investigate abnormal eating attitudes and the level of impulsiveness in morbid obese patients undergoing bariatric surgery. The present study comprised a total of 60 subjects, of whom 30 were morbid obese patients presented to the Inonu University School of Medicine, Department of General Surgery for bariatric surgery and remaining 30 were healthy controls. The participant’s abnormal eating attitudes were measured by “Eating Attitudes Test”, and the level of impulsiveness was measured by “Barratt Impulsiveness Scale (BIS-11)”. Comparing morbid obese patients with the control group, no significant difference was determined in terms of age (p=0.712). The score of abnormal eating attitudes test was significantly higher in the morbid obese patient group as compared to the control group (p=0.00). However, there was no difference between the groups in terms of the scores of Barratt impulsiveness scale (p=0.242). Individuals’ eating habit is one of the factors considered to be important for the start and maintenance of obesity. Moreover, high level of impulsiveness as well might be an important factor for the development of morbid obesity. However, in the present study, no statistically significant difference was determined between the groups despite higher scores of the patient group vs. the control group indicating the level of overall impulsiveness. Psychotherapeutic interventions focusing on impulsive characteristics and abnormal eating attitudes of the morbid obese patients might be helpful in medical and surgical treatments of these patients.

Key words: Morbid obesity, impulsiveness, eating attitudes

Med-Science. 2018; 7(2): 249-51

Gender-age distribution of tuberculosis among suspected tuberculosis cases in western Kenya

Original Article

Gender-age distribution of tuberculosis among suspected tuberculosis cases in western Kenya

Henry DN Nyamogoba, Grace Mbuthia

   

Abstract
Globally, tuberculosis (TB) continues to exact an unacceptably high toll of disease and death among children, particularly in the wake of the HIV epidemic. Kenya is ranked 13th among the “22 high-burden TB” countries, and 5th in Africa. To determine the gender-age distribution of tuberculosis among TB suspects in western Kenya. In a cross-sectional study carried out at 10 hospitals in western Kenya, sputa from 872 TB suspects underwent microscopy and culture on solid and liquid media. The growth was identified using the Hain’s GenoType® Mycobacterium CM and GenoType® Mycobacterium AS kits. A questionnaire was used to collect demographic data. In total, 41.4% of the TB suspects were diagnosed with mycobacterial disease (95.8% TB cases and 4.2% NTM disease cases). Hence, 39.7% of the suspects were diagnosed with TB, 61.6% males and 38.4% females. A total of 263 (76%) of the 346 TB cases accepted to be tested for HIV infection and 41.8% (110/263) were co-infected (males, 55.5%; females, 44.5%). There was no significant difference in the TB-HIV co-infection rate between genders [OR = 1.006; 95% CI: 0.671-1.508; P = 0.979]. The majority (40.9%) of the TB/HIV cases were in the 25-34-year age bracket. In general, the prevalence of TB was significantly higher in males than females (χ2 = 10.67; P = 0.001), the majority (37.0%) being in the 25-34 age-group. Children below 15 years constituted 4.9% of the cases. A high prevalence of TB was observed in this study, males in the 25-34 age-group carrying the highest burden. There is need for more efforts and resources to increase knowledge and access TB and NTM syndromes care.

Key words: Gender-age distribution, TB suspects, western Kenya

Med-Science. 2018; 7(2): 252-6

Evaluation of the incest cases in Hatay

Original Article

Evaluation of the incest cases in Hatay

Gizem Muratoglu, Adnan Celikel, Kenan Karbeyaz

   

Abstract
Incest is traditionally defined as any sexual activity between family members who are forbidden to marry by law. The inability of apply contemporary interview techniques to the victims and the fact that the family members do not cooperate due to intimacy of the event, make it difficult to determine the actual prevalence of incest cases. In this study, the aim was to determine the prevalence and evaluate characteristics of incest cases.
We examined the sexual crime cases have sent to forensic units in 4 years between 2013-2016. Demographic data and the relationship between the victims and defendants were evaluated. The Statistical Package for social Sciences (SPSS) version 20.0 was used to analyze the data.
There were 737 sexual crime cases and 57 of them (7.7%) were incest cases. Among these, 15.8% (n=9) of the victims were men and 84.2% (n=48) were women. The average age of victims was 15.3 ± 5.43. We determined that the defendant was mostly the father (n=24, 42.1%). The penetration rate was 33.3% (n=19).
Because of late notification and incidental recognition, physical examination findings usually are not detectable. Increasing the education and sensitivity of the individuals who can encounter with these cases like medical staff, teachers, etc. is an important process in the protection of children and their acceptance by society.

Key words: Incest, child abuse, sexual violence, Turkey

Med-Science. 2018; 7(2): 257-9

Body image, self-esteem and social anxiety levels in individuals with alcohol and substance abuse

Original Article

Body image, self-esteem and social anxiety levels in individuals with alcohol and substance abuse

Yeliz Aydin, Alper Evrensel, Mehmet Emin Ceylan

   

Abstract
Alcohol and substance addiction is a growing problem all over the world. Also, studies on understanding the causes of addiction as well as the treatment continue. Alcohol and substance addiction have genetic, environmental and psychological causes. The leading psychological cause is anxiety disorders. There are only a few studies in the literature regarding the body images, self-esteem and social anxiety levels in individuals diagnosed with alcohol and substance abuse. The rates obtained from these studies vary. This research is designed to determine the ratio in Turkish society. Thirty-five individuals hospitalized in NPİstanbul Brain Hospital with the diagnosis of alcohol and substance addiction and thirty-five healthy subjects without any addiction were compared in terms of body image, self-esteem and social anxiety levels. Self-esteem and social anxiety levels were found to be statistically significantly high in the alcohol and substance addiction group. There was no statistically significant difference between the addiction and control groups in terms of body image level. These results support that low self-esteem and high social anxiety may be among the factors predisposing to alcohol and substance addiction.

Key words: Alcohol addiction, substance addiction, body Image, self-esteem, social anxiety

Med-Science. 2018; 7(2): 260-4

Is circulating survivin altered in acromegaly?

Original Article

Is circulating survivin altered in acromegaly?

Esra Ademoglu, Erdal Dilekci, Zehra Candan, Suheyla Gorar, Mutlu Niyazoglu, Ayse Carlioglu, Faruk Yildiz, Idris Baydar, Abdulmuttalip Aslan

   

Abstract
Acromegaly is a chronic disorder which is characterized by growth hormone (GH) excess. In most of cases, GH hypersecretion is derived from somatotroph cell tumors. Survivin is a member of apoptosis protein family, which was recently showed to be expressed in tissue samples of different benign and malignant human tumors. This study is intended to determine circulating levels of survivin in newly diagnosed acromegaly patients with somatotroph adenomas. 19 newly diagnosed acromegaly patients with somatotroph adenomas were inclu-ded in the study. Concurrently, 19 healthy individuals were included as control group. Serum survivin levels, GH, insulin like growth factor-1 (IGF-1) and, some other biochemical parame-ters as fasting glucose, creatinine, alanine aminotransferase, cholesterol, triglyceride, high den-sity lipoprotein cholesterol, low density lipoprotein cholesterol were measured in each subject. Correlation analysis was performed between survivin and GH, IGF-1. Serum survivin levels tended to be higher in acromegaly group, but this was not reach statistical significance (p>0.05). Serum survivin levels were comparable among acromegaly patients and controls. Neither GH nor IGF-1 correlated with serum survivin. Larger scale studies are needed concerning the circulating levels of survivin in patients with acromegaly.

Key words: Acromegaly, survivin, apoptosis protein family

Med-Science. 2018; 7(2): 265-8

Stability of commonly nebulized drugs in heated and humid condition

Original Article

Stability of commonly nebulized drugs in heated and humid condition

Haitham Saeed, Mohamed EA. Abdelrahim, James Fink

   

Abstract
Placement of nebulizer prior to heated humidifier has been reported to improve efficiency of aerosol delivery during ventilator support. Drugs nebulized in this position must travel through humidifier, rainout in reservoir and may be subjected to extended periods of heat up to 50°C. Toxic degradation may develop, posing potential risk to patient. The aim of this study was to evaluate chemical stability of commonly inhaled drugs administered to mechanically ventilated patients subjected to extended period of 50°C. Formulations of 8 comonly inhaled drugs were diluted to 50 mL total volume in water and exposed to 50oC for 7 days to simulate effect of heat in humidifier. High Performance Liquid Chromatography (HPLC) was performed before and after heating to determine drug stability and degradation. Drug integrity, color or pH changes were noted. Epinephrine, levalbuterol, tobramycin and colistin demonstrated>10% reduction in concentration but only acetylcysteine had additional peaks in HPLC chromatogram demonstrating potential degradation and possible production of by product. Changes in color were observed with epinephrine and acetylcysteine.
All drugs retained their integrity after subjecting them to 50oC for 7 days except acetylcysteine. Acetylcysteine changed color and had new peak in HPLC chromatogram. Color change with epinephrine was not associated with any new peak in HPLC chromatogram. Further studies should determine whether acetylcysteine changes would result in any off gassing of vapor that might harm the patient.

Key words: Ventilation, nebulizer, respirable medication, heat, humidity, humidifier

Med-Science. 2018; 7(2): 269-76

The opinions about euthanasia among students in elderly care department of vocational school of health services at Bingol University

Original Article

The opinions about euthanasia among students in elderly care department of vocational school of health services at Bingol University

Aliye BULUT

   

Abstract
This study was conducted in order to collect information about the current knowledge, attitudes, and beliefs of the students, studying in the elderly care department of Vocational School of Health Services in Bingöl University, about euthanasia and determine the related problems if any. The population of this descriptive study consisted of students studying in Elderly Care department of Bingöl University, Vocational School of Health Services. The data collection tool used in the study was the Questionnaire developed by the researcher based on the literature information. The Questionnaire involves 33 questions. It was determined that 75.2% of the participants thought that their knowledge about euthanasia was sufficient, 20.5% did not consider that their knowledge level was enough. While 85.5% of the participants never encountered euthanasia request in their professional life, 5.1% encountered several times. In accordance with the obtained results, it is recommended to discuss euthanasia by being considerably involved in elderly care curriculum and conduct qualitative studies about euthanasia.

Key words: Euthanasia, opinions on euthanasia, elderly care students

Med-Science. 2018; 7(2): 277-82

The evaluation of the forensic reports referred to the council of forensic medicine, Yalova region, Turkey, 2014-2016

Original Article

The evaluation of the forensic reports referred to the council of forensic medicine, Yalova region, Turkey, 2014-2016

Zeynep Yener

   

Abstract
The aim of this study was to determine the demographic and referral-related characteristics and the conclusions of the legal reports which were referred to the Council of Forensic Medicine, Yalova. Legal reports of cases who were referred to the Council of Forensic Medicine in Yalova from 01.01.2014 to 31.12.2016 were reviewed. A retrospective evaluation regarding the application year, age and gender of the applicant, the referring department, the inquiry in terms with the Turkish Penal Code, whether the case was examined in person and the conclusion of the report, was performed. 398 cases (39.9%) in 2014, 454 cases (40.9%) in 2015 and 257 cases (23.2%) in 2016 were referred to the Council of Forensic Medicine in Yalova. These cases included 889 (80.2%) men and 220 (19.8%) women. For most of the cases (34%), the age range was 11-20 years. The most common referral reasons were injuries due to battery (31%) and evaluation of cases with regards to the criminal liability and the juridical capacity. Most of the reports were requested by the Office of Public Prosecutions. Physical examination was performed in 726 cases (65.5%) while 383 (34.5%) reports were written solely depending on the evaluation of documents. Male gender, young age, legal report requests for malicious wounding and needlestick and sharp object injuries were the most common characteristics of the legal reports conducted in our district in the 3 year period. Regional profile and database administration could be useful in decreasing or preventing the legal incidents as well as the better planning and performance of the Forensic Medicine Services.

Key words: nsic Medicine, legal reports, legal cases

Med-Science. 2018; 7(2): 283-9

Postoperative complications in total intravenous anesthesia with propofol compare with sevoflurane anesthesia: A retrospective study

Original Article

Postoperative complications in total intravenous anesthesia with propofol compare with sevoflurane anesthesia: A retrospective study

Ozlem Kocaturk

   

Abstract
The aim of us is to define the incidence of postoperative complications two anesthesia procedures. During the period between 01.01.2016 and 01.01.2017, totally 583 patients were included in the study, who had oral-maxillofacial surgeries. Anesthesia types were determined as propofol-based total intravenous anesthesia (TIVA) and sevoflurane-inhalation anesthesia (SA). Surgical types were divided into two groups, major and minor. Postoperative complications and recovery period were determined as tachycardia, bradycardia, hypertension, hypotension, recovery time, additional analgesia, nausea-vomiting.
While TIVA was used 241 patients, SA was used 342 patients. Incidences of patients, having had major surgeries under TIVA, for additional analgesic, nausea-vomiting, and recovery period on average were found as 12.7%; 13.5%; 13min respectively. As for the patients having had minor surgeries under TIVA, the same values were 10.2%; 6.5%; 12min respectively. Incidences of patients, having had major surgeries under SA, for additional analgesic, nausea-vomiting, recovery period on average were found as 11.3%; 34.2%; 7min respectively. Patients having had minor surgeries under TIVA performed the same values as 9.8%; 19.5%; 5min respectively.
It was observed that SA caused more nause-vomiting than TIVA; however, it had a shorter recovery period. We have been in the opinion of that SA absolutely must be done with nausea-vomiting premedication and that it could be preferred owing to the shorter recovery.

Key words: Sevoflurane Anesthesia, Total intravenous anesthesia (TIVA), maxillofacial surgery, Ppostoperative complications, recovery period

Med-Science. 2018; 7(2): 290-4