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Bell’s palsy: A clinical study of management and outcomes

Original Article

Bell’s palsy: A clinical study of management and outcomes

Selcuk Kuzu, Caglar Gunebakan

   

Abstract
Facial nerve palsy might be observed for various reasons. The majority of facial paralysis appears as “idiopathic” or “Bell palsy”. Of the patients, approximately 80-85% experience spontaneous and complete recovery within the first three months in Bell’s palsy. However, it is an accepted fact that these patients should be diagnosed correctly and initiated treatment in the early period. The study aimed to make a retrospective analysis of the treatment modalities and results of patients diagnosed with Bell’s Palsy in a tertiary hospital clinic and discuss the subject in the light of current literature.

Key words: Facial paralysis, bell’s palsy, diagnosis, management modalities

Med-Science. 2020; 9(4): 939-49

 
 
Medicine Science Vol:9 Issue:4 Year:2020 PP:802–1112

Caregiver burden and affecting factors for patients with schizophrenia

Original Article

Caregiver burden and affecting factors for patients with schizophrenia

Recep Basaran, Ikbal Inanli, Ibrahim Eren, Ismet Esra Cicek, Ali Metehan Caliskan, Bilge Cetin Ilhan, Senay Yildiz Bozdogan, Mustafa Cagri Yildiz

   

Abstract
Caregiver burden is a complex concept that is influenced by many different factors. This study aimed to evaluate caregiving burden in caregivers of schizophrenia patients and to examine the effect of gender and other socio-demographic and clinical characteristics on caregiving burden. This study included 100 (50 female, 50 male) patients, who had been diagnosed with schizophrenia and their caregivers. The Zarit Caregiver Burden Scale (ZCBS), Hamilton Anxiety Rating Scale (HAM-A), Hamilton Depression Rating Scale (HAM-D), and Symptom Checklist-90-Revised (SCL-90-R) were administered to the caregivers. Insight Rating Scale (IRS), Calgary Depression Scale for Schizophrenia (CDSS), Positive and Negative Syndrome Scale (PANSS), Functional Recovery Scale in Schizophrenia (FRSS), Global Assessment Scale (GAS) were administered to the patients. The caregivers of male patients had significantly higher HAM-A, HAM-D, ZCBS total and all subscale, and SCL-90-R total and all subscale scores. The male patients had significantly higher PANSS general psychopathology subscale and CDSS and lower IRS scores. Multiple regression analysis revealed that male patient gender, living in urban areas and HAM-D scores of the caregivers were predictive of ZCBS total scores. This study found that schizophrenia has a significant burden. In addition, male patient and depression level of the caregivers were determined as the predictors of the caregiven burden.

Key words: Schizophrenia, caregiver, burden, gender

Med-Science. 2020; 9(4): 806-13

 

Morphometric anatomic study and clinical significance of the collateral ligaments of the thumb interphalangeal joint

Original Article

Morphometric anatomic study and clinical significance of the collateral ligaments of the thumb interphalangeal joint

Merve Onder, Cengiz Aldemir

   

Abstract
We aimed to emphasize the clinical significance of the collateral ligaments of the thumb interphalangeal joint through a morphometric anatomical study. Our study was performed on the thumbs obtained from 10 fresh cadavers in Akdeniz University Faculty of Medicine Anatomy Department Laboratory. The collateral ligaments in the thumb interphalangeal joint were examined and morphometric analysis was carried out using MicroScribe G2X. It was observed that the collateral ligaments are made up of proper (pCL) and accessory (aCL) components. pCL extends from the dorsal surface of the proximal phalanx head to the palmar surface of the proximal end of the distal phalanx, while aCL extends obliquely from dorsal to palmar and from proximal to distal and attaches to the palmar plate. The mean vertical and transverse diameters of the collateral ligament in the proximal interphalangeal joint were 12±2 mm (10 mm min –14 mm max) and 3±1 mm (2 mm min – 4 mm max), respectively. Knowing the anatomy and morphometry of the collateral ligaments of the thumb interphalangeal joint will shed light on the surgical techniques that are to be applied in the reconstructions of injured ligaments.

Key words: Thumb, collateral ligament, interphalangeal joint

Med-Science. 2020; 9(4): 814-6

 
 
 

Assessment of sertraline activity in a vasospasm model following experimental subarachnoid haemorrhage

Original Article

Assessment of sertraline activity in a vasospasm model following experimental subarachnoid haemorrhage

Veysel Kiyak, Mustafa Namik Oztanir, Nese Basak Turkmen, Asli Tasdemir, Osman Ciftci

   

Abstract
Vasospasm following subarachnoid haemorrhage (SAH) is a process yet to be fully clarified in terms of its aetiology and results. According to one of the many theories about vasospasm developing after SAH, the process results from an increase of pro-inflammatory agents and decrease in antioxidant agents. Other hand experimental studies on rats found a significant decrease in the pro-inflammatory parameters TNF-α and IL-1β in the blood values obtained after the use of sertraline. In this study, the findings regarding the effectiveness of sertraline in the treatment of vasospasm developing an experimental SAH model are presented. In this study, adult males of Spraque-Dawley breed, not used in any previous study and weighing between 250–350 g, were used. Rats were divided into 4 groups with the control group (n=5) and other groups (n=6 in each). Group 1 was the control, and Group 3 was the sertraline group. In Groups 2 and 4, SAH was initiated by giving rats autologous arterial blood in the cisterna magna. The tissues were examined in terms of mononuclear cell infiltration, vascular congestion, and neuron degeneration. In the experimental SAH model based on these values, it was found that the use of sertraline significantly reduced mononuclear cell infiltration, vascular congestion, and neuron degeneration. Moreover, in animal studies, it was shown that SSRIs increased neurogenesis and release of neurotrophins from the hippocampus. In our study, it was concluded that sertraline was effective in dissolving vasospasm in the experimental SAH model. However, we further believe that more experimental studies to investigate other SSRI compounds of the same family can contribute to the knowledge and understanding of this process.

Key words: Sertraline, vasospasm, subarachnoid haemorrhage

Med-Science. 2020; 9(4): 817-22

 
 
 

Investigation of the effect on prostate cancer purine base analog of the newly developed compound

Original Article

Investigation of the effect on prostate cancer purine base analog of the newly developed compound

Gokhan Temeltas, Funda Kosova, Ozlem Temiz Arpaci, Ibrahim Tuglu

   

Abstract
Prostate cancer is an important cause of death in men. This malignant disease is known for excessive proliferation, decreased apoptosis, and uncontrolled proliferation of cells. In the light of this knowledge, our aim was to examine potential compounds for their effects on NF-κB and angiogenesis proteins (VGEF, MMP, ES, TSP-1) in a prostate cancer line. In this study, we planned that the purine base analogue with anti-cancer potential has synthesized new compounds, and those with anti-cancer potential has selected by screening with MTT testing. We analysed VEGF, MMP, Endostatin (ES), Thrombospondin-1 (TSP-1) and NF-κB protein levels in a prostate cancer line by the Elisa method. MMA-MEP caused a significant decrease especially for VEGF-A, NF-kB, Endostatin, Thrombospondin -1 and MMP levels compared to other compounds.
This suggests that this heterocyclic compound is more effective compared to others. This compound could be more effective for patients with prostate cancer, depending on time and amount. In line with these results, we want to continue our work by applying this heterocyclic compound in different amounts at different time periods.

Key words: Prostate cancer, NF-kB, VEGF, MMP, endostatin and thrompospondin-1

Med-Science. 2020; 9(4): 823-8

 
 
 

Health perceptions and healthy lifestyle behaviors of Erciyes University students

Original Article

Health perceptions and healthy lifestyle behaviors of Erciyes University students

Belgin Oral, Fevziye Cetinkaya

   

Abstract
The aim of this study is to determine some factors that may be related to the health perceptions and healthy lifestyle behaviors of Erciyes University students. In this descriptive research, 1286 students from the first and fourth-year students studying in the undergraduate programs at the Faculty of Medicine, Engineering, Education and Literature of Erciyes University were included. For the socio-demographic data, the Health Perception Scale (HPS) and the Healthy Lifestyle Behaviors Scale (HLBS) were used with a questionnaire consisting of 31 questions. 60.9% of the students included in the research were women, the average age of the whole group was 21.1 ± 2.4 years. 50.9% of students in the Faculty of Medicine, Engineering, Education, and Literature were first-year students. HPS scores of the students were found to be 40.7 ± 6.2 and HLBS scores as 125.4 ± 19.5. University students’ perceptions of health were found as low and healthy life behaviors were moderate. İn order to provide the development and maintenance of positive perceptions of health perception and healthy lifestyle behaviors, and the positive interaction of these two phenomena, individual and social support is needed for the students.

Key words: University student, Health Perception, Healthy lifestyle behaviors

Med-Science. 2020; 9(4): 829-36

 

The effects of physiotherapy methods combined with respiratory and relaxation exercises on patients with major depression

Original Article

The effects of physiotherapy methods combined with respiratory and relaxation exercises on patients with major depression

Elisa Calisgan, H Birgul Cumurcu, Burcu Talu, Esra Porgali Zayman, Yusuf Aydin

   

Abstract
This study aimed to evaluate the effects of physiotherapy methods combined with respiratory and relaxation exercises on patients with major depression. This randomized, controlled trial included 42 patients with a sedentary lifestyle, comprising 21 males and 21 females with a mean age of 37.78±11.67 years (range, 20-60 years). The experimental (n:22)and control groups (n:20) were evaluated using the Beck Depression and Anxiety Score, Visual Analog Score, Patient Health Questionnaire-15, Generalized Anxiety Disorder 7-Items, and Patient Health Questionnaire-9. In both the experimental group and control group, a statistically significant difference was found in all parameters over time, with greater improvements made in the experimental group than in the control group in all the parameters. A rehabilitation program combined with respiratory and relaxation exercises applied in addition to standard treatment, can obtain more successful outcomes in major depression treatment.

Key words: Major depression, physical exercises, respiratory, relaxation, antidepressant

Med-Science. 2020; 9(4): 837-43

 
 
 

Investigation of demodex spp prevalence in medical laboratory students

Original Article

Investigation of demodex spp prevalence in medical laboratory students

Ahmet Yilmaz, Onder Akkas

   

Abstract
This study focused on the prevalence of Demodex spp. in the students at Igdir University Vocational School of Health Services (VSHS) and on possible factors for this occurrence.The study was conducted with a total of 171 students (in the 18–52 age group, mean age: 21.33±3.14, of whom 73 were male and 98 were female) between January 2018 and May 2018. Samples were taken from the students’ faces – especially the nasal root, forehead, and cheeks – using the cellophane tape method. The samples were analyzed under a microscope, without dyeing,at 10X and 40X magnifications. To discover possible causes for the Demodex spp. prevalence, a survey was given to the same students.In this investigation, 59 out of 171 students were found to have Demodex spp. There was no immediate relationship between the prevalence of Demodex spp. and variables such as gender, age, family type, the presence of chronic disease, or facial hygiene. However, the ratio of Demodex spp. prevalence reached 19% in students who habitually ate dried nuts and fruits compared to those who did not.We concluded that the Demodex spp.the infestation was very high in students at VSHS. We also detected a negative correlation between the prevalence of Demodex spp. and the habit of eating dried nuts and fruits.

Key words: Demodex spp, prevalence, infestation, risk factors

Med-Science. 2020; 9(4): 844-7

 
 
 

Attitudes of nursing and medical school students towards ageism

Original Article

Attitudes of nursing and medical school students towards ageism

Medine Koc, Aygul Kissal, Riza Citil, Yalcin Onder

   

Abstract
The present study aimed to evaluate the attitudes of nursing and medical school students towards age discrimination and to determine the association between these attitudes and various variables. A total of 662 students, 328 from the Faculty of Nurse Education and 334 from the Faculty of Medicine, participated in the present descriptive and cross-sectional study.Data were collected using Data Form for socio-demographic characteristicsand Ageism Attitude Scale (AAS). Descriptive statistics, t-test, Mann-Whitney U test, Chi-square test, One-Way ANOVA, and Kruskal Wallis test were used to evaluate the data using IBM SPSS Statistics for Windows (Version 20.0).Nursing school students had higher points in “restricting the life of elderly people”, “positive discrimination towards them” and Ageism Attitude Scale, but had lower points in “negative discrimination towards them” compared to medical school students. While the points of “positive discrimination towards elderly” and Ageism Attitude Scale of the students of two schools were not significantly different (p>0.05), points of “restricting the life of elderly people” and “negative discrimination towards elderly” varied significantly between the students of two schools (p

Key words: Student, elderly, ageism, attitude

Med-Science. 2020; 9(4): 848-55

 
 
 

Domestic violence and affectıng factors among married women aged between 15-49 Years

Original Article

Domestic violence and affectıng factors among married women aged between 15-49 Years

Sema Ciftci, Yasemin Acik

   

Abstract
Domestic violence against women is an important public health problem commonly encountered in all societies, manifesting itself as a negative outcome of gender inequality. This study has been carried out in Mardin province to determine the prevalence of exposure to domestic violence among women aged between 15-49 years and the affecting factors. The population of the study consisted of the women aged between 15-49 years living in Mardin and 1111 people were selected for sampling. Through repeated visits, 1064 people were included in the study (the responsiveness rate was 95.8%). x² (chi-square) test was used in the statistical analysis. The average age of women was 32.5 ± 8.2. 29.4% of them were illiterate. 47.5% of them were married by prearrangement. 25.9% of them were subjected to physical violence by their father and 37.6% by their mother in the past. The women were exposed to physical (44.5%), verbal/emotional (56.4%), economic (37.7%), and sexual violence (14.8%) at least once in their lifetime. 13.2% of them are still exposed to domestic physical violence, 15.8% to verbal/emotional violence, and 7.3% to sexual violence. As the educational levels, socioeconomic status, and monthly income of women and their husbands decrease, the rate of exposure to violence increases (p

Key words: Domestic violence, Mardin, women,

Med-Science. 2020; 9(4): 856-65