Identification of marker proteins in preterm and term birth: Relationship of rankl and HSP70 in the cord blood
The goal of this research was to investigate at the expression profiles of heat shock protein 70 (HSP70) and receptor activator of nuclear factor-kappa B ligand (RANKL) in term and preterm infants. Preterm birth (n=13) and term birth (n=13) cord blood samples were studied. In the cord blood serum protein expression levels of the HSP70 and RANKL were measured by ELISA. When compared to the term birth group, preterm birth had greater RANKL concentrations. When comparing the preterm birth study group to the term birth study group, protein expression of HSP70 and RANKL was not shown to be associated. These results indicate that HSP70 and RANKL levels in cord blood may affect both prenatal and postnatal treatment approaches.
Keywords: RANKL, HSP70, preterm birth, term birth
Conflict of Interests: The authors declare that they have no competing interests.
Financial Disclosure: All authors declare no financial support.
Ethical Approval: The current study was confirmed by Ethical Committee of Usak University of Medical Sciences (Reference Number: 214-08) and written informed consents were obtained from all participant’s parents.
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Uzunok B, Gurel S. Identification of marker proteins in preterm and term birth: Relationship
of rankl and HSP70 in the cord blood. Med Science. 2022;11(2):462-4
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Corresponding Author: Selcuk Gurel, Usak Oztan Hospital, Department of Pediatricians, Usak, Turkey