Comparison of the algan hemostatic agent with celox in rat femoral artery bleeding model
Kenan Binnetoglu, Ali Kumandas, Husamettin Ekici, Abdullah Canberk Ozbaykus, Mehmet Tiryaki
The most important reasons of deaths after a trauma are major vascular injury. The effective and speedy control of the hemorrhage is crucial in reducing such deaths. Although many products are being used for this topic, most effective products have not yet been developed currently, and there is an urgent need for effective hemostatic. The aim of this study is to compare the efficacy of Algan hemostatic agent (AHA) with Celox in femoral artery incision model in rats. A total of 28 wistar albino rats divided into 4 equal groups. Experimental femoral artery injury was inflicted. In the control group, saline impregnated gauze was employed. AHA impregnated sponge, AHA powder, and Celox in powder form were utilized in the experimental groups. According to the results, there was no difference in bleeding control between AHA and C (p>0.05). When compared to the control group, AHA and Celox were found to be very effective in bleeding control (p<0.001). This study showed that AHA had a similar effect like Celox in controlling bleeding. Considering other characteristics such as AHA’s naturalness, easy applicability and low cost, AHA has given hope as an effective hemostatic agent.
Key words: Femoral artery, hemorrhage, bleeding, algan hemostatic agent, celox