Relationship between systemic immune inflammation index and systemic inflammation response index values and prognosis in patients with burns

To determine the relationship between systemic immune inflammation index (SyII) and systemic inflammation response index (SyIRI) values and prognosis in adult and pediatric cases treated for deep partial thick and full thick burns. A total of 358 cases were enrolled in the study, and their SyII and SyIRI indices at the time of hospital admission were retrospectively calculated using medical record data. The mean SyII (4610.7 vs. 1874.9; p=0.001) and SyIRI (20.8 vs. 7.3; p<0.001) values in the deceased group were notably higher than in the surviving group. SyII (p=0.006 and p<0.001, respectively) and SyIRI (p<0.001 for both) values were found to be independent risk factors in terms of both hospital stay longer than 30 days and mortality. SyIRI and SyII values of those with electrical burns were 4.7 ± 4.7 and 1507.2 ± 1380.4, respectively. SyIRI and SyII values of those with thermal burns were 8.7 ± 11.7 and 2147.8 ± 2711.4, respectively. A statistically significant difference was observed in SyIRI values between thermal and electrical burns (p=0.034), while SyII values did not differ significantly. The study shows that the risk of prolonged hospital stays, and mortality is higher in cases with severe burns with higher SyII and SyIRI values measured at the time of admission to the hospital. However, in terms of burn types, SyIRI is a more effective marker in distinguishing thermal burns from electrical burns.