The utility of serum calcium and phosphate levels for determining mortality in patients with acute ischemic stroke

The most common form of stroke presents as ischemic stroke. For these patients, the primary goals of stroke management in the emergency department are revascularization and minimizing secondary neuronal damage via thrombolytic therapy and/or endovascular thrombectomy. However, in addition to improvements in the treatment of stroke, preventive measures to avoid stroke occurrence have been the focus of considerable recent research interest. Calcium and phosphorus are important elements in many structural components and cellular processes in the body. The aim of the study was to evaluate the role of serum calcium and phosphorus levels on the mortality of patients with acute ischemic stroke (AIS). The data of 1,204 patients admitted to the emergency department of our secondary state hospital between 2019 and 2021, and subsequently hospitalized for diagnosis of AIS, were analyzed. Our results showed that low serum calcium levels associated with mortality in AIS patients, but  phosphate levels have no effect on mortality of patients with AIS.