Retrospective comparison of ALT-AST values of patients before and after the COVID-19 period in Ardahan province

The primary purpose of this study was to evaluate the significance level between the liver damage marker (ALT-AST) levels taken in both periods from individuals who came to Ardahan State Hospital before and after the coronavirus disease of 2019 (COVID-19) disease period that appeared in our country in March 2020. Patients with chronic viral infections, alcohol use problems, liver cancer, chronic liver disease and cirrhosis were excluded from the study. Considering the period of March 2020, which was the first time it was seen in our country, liver marker levels of the same patients were examined in both periods, before and after. Statistical significance levels were evaluated and discussed in the literature. It was determined that 68 of 96 individuals (70.8%), whose ALT and AST enzyme levels were examined before and after COVID-19, had an increase in ALT and AST levels compared with the pre-COVID-19 period. The COVID-19 pandemic, a new era in human life, continues even though it has lost its effect. These effects include the stress of the illness period, the side effects of the medications used and the permanent damage caused by the COVID-19 infection. Because of these results, liver checquese and orientation towards a healthy life are of great importance after the COVID-19 period.