Evaluation of hemogram parameters in patients with deep vein thrombosis and pulmonary thromboembolism

Deep vein thrombosis (DVT) and pulmonary embolism is defined as venous thromboembolism (VTE). Deep vein thrombosis is the most common in lower extremity veins, it is seen in the upper extremity veins, more rarely. In this study we aimed to research the values of NLR, PLR, PCT and PDW in DVT and pulmonary thromboembolism (PET). Our study is the only study in which these parameters are examined together. Patients’ gender, age, pulmonary embolism history, medications used, hospitalization history and hemogram values are recorded. Extremity involvement findings, neutrophil lymphocyte ratio (NLR), platelet lymphocyte ratio (PLR), plateletcrit (PCT) and platelet distribution width (PDW) is recorded. The mean age of patients was 60±19.83. Eigtheen (10.2%) of the patients had a history of recurrent deep vein thrombosis. 30 (16.9%) of the patients with deep vein thrombosis have pulmonary thromboembolism. While 94 (53.1%) patients with deep vein thrombosis had left lower extremity involvement, 39 (22%) had right lower extremity involvement. 52 (29.4%) patients were hospitalized, and 81(60,9%) patients were followed up outpatient. 44 (33.1%) patients had warfarin treatment, and 89 (%66.9) patients had DMAH treatment. NLR, PLR, PDW, PCT were 5.84 (min0.35- max 0.10), 181.26±144.14, 12.31±2.82, 0.25 (min0.00-max0.50) respectively in DVT, 7.32 (min 0.35-max34.5), 184.97±130.06, 11.93±1.95, 0.22 (min0.08-max0.39) respectively in PTE. In the light of the data obtained, we believe that hemogram parameters are appropriate markers for the prediction of DVT and PTE patients and/or inflammatory response during DVT and PTE. However, there is a need for more comprehensive studies on the course of the disease and the value of these markers.

Keywords: Hemogram parameters, deep vein thrombosis, pulmonary thromboembolism